In 2002, University of California at Davis researchers published a well-publicized paper noting that Americans' increasing consumption of fructose, including that in HFCS, paralleled our skyrocketing rates of obesity.
What science really really found was that both HFCS and sucrose, better known as table sugar, contain similar amounts of fructose. Sucrose is almost chemically identical, containing 50 percent fructose. The truth is, there's no evidence to show any differences in these two types of sugar. Both will cause weight gain when consumed in excess, not good for fat loss.
The bottom line: For fat loss, HFCS and regular sugar are empty-calorie carbohydrates that should be consumed in limited amounts. How? By keeping soft drinks, sweetened fruit juices, and prepackaged desserts to a minimum.